Centre considering removing plasma therapy from COVID-19 clinical management protocol

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The Centre is considering to remove convalescent plasma therapy from the national clinical management protocol for COVID-19, a top ICMR official said on Tuesday. Presently, the use of off-label convalescent plasma for treating COVID-19 patients in the moderate stage of the illness is allowed under "investigational therapies".

However, a randomised controlled trial, led by the Indian Council of Medical Research (ICMR), on 464 patients in 39 hospitals in 25 districts across 14 states and UTs has shown that plasma therapy does not reduce mortality or prevent progression of COVID-19 from moderate to severe.

At a press conference, ICR Director General Balaram Bhargava said, "We have had discussions in the national taskforce and we are in discussion with the joint monitoring group that this (convalescent plasma therapy) may be deleted from the national guidelines. The discussion is ongoing and more or less we are reaching towards that."

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